So based off your summary, I think the best place to start would be some comedy or character driven past-scenes. Maybe doing a quick scene of Myra and Lauren meeting in college in some funny way- maybe to avoid an awkward conversation one of them asks the other to pretend to be friends, or they rear end each other, or one of them is a campus parking enforcer and the other gets a ticket, or one of them always gets the same bagel from a campus food store and the other works there. Something light that, then a narration saying “five years later” and showing them in their apartment together- continue story 
But your first few scenes should Myra (the main character I think?) as a character. I noticed you said a lot about what people’s jobs were, but what is Myra like? Is she quiet, sarcastic, scattered, enthusiastic, jaded? Who is she and how does she act? Why does Lauren like her?