Ok, I’m going to tell you the first idea that came to my mind when I read the title.
MC is a beautiful girl, but she is really girly. She likes pink, puppies, fancy clothes etc.
She meets a guy (the LI) and falls head over heels in love with him. The only problem is that he is a biologist who is specialised in research on “beautiful creatures”: spiders, snakes, lizzards (it could be anything). The MC is really scared of them but learns to appreciate them in the end.
Throughout the story you could make the MC watch the favorite spider, snake, luzzard of the LI while he is away and the it escapes or something. I think that you can come up with a lot of funny situations the MC gets herself in to.
Well it’s just an idea. Feel free to use it, or not hahaha.